Application of Ultrasonic Extrusion in the Preparation of Liposomes

摘要：

Liposomes have a wide variety of applications inBiomedical Engineering, such as in vaccines, geneticengineering, anti-cancer drugs and drug controlled releasesystems. Traditional preparation methods produce liposomeswith a wide size distribution and elaborate processes are neededto produce narrow size distributions. The research presentedhere, attempts to improve the traditional preparation methodsfor liposomes using a nano-liposome preparation method thatuses ultrasonic extrusion. Ultrasonic extrusion is performedhere with a transducer device at the frequency of 135 kHz.Nano-liposomes can be prepared through extrusion in acontinuous process where the nano-liposomes can be collected asa suspension without the use of any surfactants.

作者: Ioannis Manousakas Guan-Huei Lin Shwu-Jen Chang Shyh-Ming Kuo Yu-Chiuan Wu

作者单位: Department of Biomedical Engineering I-SHOU University Taiwan Department of General Surgery Kaohsiung Armed Forces General Hospital,Department of Electrical Engin

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）