synthesis of water-soluble quaternized chitosans and their antitumor activity

摘要：

water-soluble low-molecular-weight chitosan(LCTS)was prepared by hydrogen peroxide oxidation method and theirquaternized derivatives(QLCTS) was also synthesized usingprevious methods. Their antitumor activity was studied, and theresults showed that the LMW and its quaternized derivativesinhibited the growth of pancreatic carcinoma cell strain PANC-1in vitro, and the inhibitory rate reached 59.2%.

作者: Fang Dong Qinzhao Xue Jingli Liu Jianming Ren Zhanyong Guo

作者单位: Yantai Institute of Coastal Zone Research for Sustainable Development, CAS, Yantai, 264003, China In Yantai Institute of Coastal Zone Research for Sustainable Development, CAS, Yantai, 264003, China Yantai Institute of Coastal Zone Research for Sustainable Development, CAS, Yantai, 264003, China Gr

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-3

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）