Experimental research on the cytotoxicity of CdSe nanocrystals with the irradiation of violet light

摘要：

The present study processed the absorption spectrumof CdSe nanocrystals (Ncs) which was modified bymercaptoacetic acid (MA). Based on this, the LEDs whoseemission peak is near the absorption peak of the NCs wereselected to form a LED array. The leukemia cell line HL60 wascultured in two 96-well plates and incubated with differentconcentrations of MA-Coated CdSe NCs. One of the 96-wellmicroplates was irradiated by the LED array mentioned above,and the other wasnt. Then the viability of the cells on bothmicroplates was determined using CCK-8 assay. The results invitro demonstrated that the ability of MA-Coated CdSe NCs toinduce cell death can be promoted under the irradiation of thelight source we used.

作者: Li Chen Jing Zuo Hua Xiao Jianwen Xiong

作者单位: School of Physics & Optoelectronic Engineering, Guangdong University of Technology Guangzhou, China School of Physics and Telecommunication Engineering,South China Normal University Guangzhou, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-3

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）