Geometric calibration method based micro-CT system for small-animal imaging
Small-animal imaging technology has been rapidlydeveloped for longitudinal screening of laboratory animalsraised with disease developments or genetic manipulations.Micro-CT is a noninvasive imaging modality used to assessmorphology and function in small-animal imaging. Geometriccalibration involves the estimation of a set of parameters thatdescribes the geometry of such systems, and is essential foraccurate image reconstruction. Noo F et al (2000) have proposeda new analytic method for calibration of x-ray cone-beamscanners that use a circular path for the cone vertex. In thispaper, we use this analytic calibration method for the estimationof the geometric parameters of a practical small-animal imagingmicro-CT system. We improve calibration phantom of thismethod in order to make it more suitable for micro-CT system.The overall performance of the micro-CT system isdemonstrated in some results of small-animal imaging. Theprojection images demonstrated that the adopt method is robustand easy to implement with high precision.
Zhanli Hu Jing Zou Jianbao Gui Junyan Rong Yanming Li Hairong Zheng
Paul C.Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China Key Lab for Biomedical Informatics and Health Engineering, C
国际会议
成都
英文
1-4
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）