Microarray Images Processing Using the Offset Vector Field and Expectation Maximization Algorithm

摘要：

DNA microarrays provide a simple tool to identify andquantify the gene expression for tens of thousands of genessimultaneously. Image processing is an important step inmicroarrays experiments. This paper presents a novel techniquefor removing genes noises based on the offset vector field andsegmenting genes using the expectation maximization algorithm.Simulations show that the new technique for microarray imagesfiltering and segmentation has better performance than most of thecommon ways. The results of experiments are computationallyattractive, have excellent performance and can preserve spotsdata while efficiently suppress noises.

作者: Weng Guirong Su Jian

作者单位: School of Mechanic & Electronic Engineering, Soochow University, Suzhou 215021 China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-3

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）