A Feldkamp-type approach to limited-angle on-board three-dimensional imaging for external beam radiotherapy target localization

摘要：

Accurate three-dimensional tumor localization inradiotherapy is critical to the treatment outcome, particularlywhen high dose gradients are present. Digital tomosynthesis(DTS) is a method to reconstruct three-dimensional (3D) imagesfrom two-dimensional (2D) x-ray projections acquired overlimited scan angles. In this study, we have used a Feldkamp-typeapproach to reconstruct DTS images. The accuracy of thereconstruction was evaluated by computing the pixel signal-to-noiseratio (PSNR) and the mutual information (MI) sharedbetween DTS images and 3D cone-beam computed tomography(CBCT) images. The results indicate the DTS slices appearedsimilar to coincident CBCT planes and yielded substantiallymore anatomic information than conventional kilovoltage (kV)verification radiographs, but required a lower imaging dose,faster acquisition, and more geometric flexibility than CBCT.

作者: Ya_chong Feng Ling_hong Zhou Xin Zhen Wen_ting Lu

作者单位: School of Biomedical Engineering, Southern Medical University Guangzhou, 510515, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-3

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）