Application Study of Using Ultrasonic Integral Backscatter to Monitor Microwave Coagulation Therapy
Microwave (MW) ablation is a minimallyinvasive therapeutic strategy for the local treatment ofsolid malignancies that has received much attention over the past few years. It is very important to detect andevaluate lesions generated by MW during treatmentprocedures. This study describes one new ultrasonicimaging technique to characterize lesions based onestimation of relative changes in tissue properties derivedfrom backscattered RF data. A single microwave heatingantenna was used to produce coagulation in vitro pig livertissues. The RF signals were recorded as outputs from amodified diagnostic ultrasound system. The integratedbackscatter values, which can be used as an indicator of the microstructure and backscattering property of tissues,were calculated in water-bath experiment and Mwtreatment. The rule of change in integrated backscattervalues with temperature has been analyzed by statisticsthrough water-bath experiment. The integratedbackscatter ratio values were subsequently used to formimages revealing the lesion areas. It is possible usingultrasonic integral backscatter to monitor microwavecoagulation. The result shows that this approach can beused to identify the normal and coagulated tissue causedby temperature rise and provide the information of tissuedamage.
Sheng Lei Yang Chunlan Wu Shuicai Bai Yanping Zeng Yi
Biomedical Engineering Center, Beijing University of Technology,Beijing 100124, China
国际会议
成都
英文
1-4
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）