Study on Noninvasive Auto-estimation of Pulmonary Vascular Resistance by Doppler Audio-signal Processing System

摘要：

Objective: To assess the feasibility andaccuracy of Doppler audio-signal Processing system(DASPS) in noninvasive automatic estimation ofpulmonary vascular resistance(PVR). Methods: PVRwas estimated with DASPS in 32 children withleft-to-right shunting congenital heart disease,compared with those estimated by Dopplerechocardiography and cardiac catheterization. Results:PVR estimated by DASPS adopting aorta, pulmonaryartery, pulmonary venous and mitral flow timeintervals highly correlated with those measured bycardiac catheterization (r=0.93, p<0.001), better thanthose measured by Doppler echocardiography (r=0.79,p<0.01). The time for estimating PVR with DASPSwas shorter than with Doppler echocardiography(7.1±2.3 min vs 57.5±16.5min, p<0.05), therepeatability for DASPS was better than for Dopplerechocardiography (p<0.05). Conclusion: PVR couldbe accurately quantitatively, noninvasively,auto-estimated by DASPS.

作者: Yuqi Zhang Zhiqing Yu Yuanyuan Wang Weiqi Wang Zhifang Zhang Yu Ma

作者单位: Department of Pediatric Cardiology, Shanghai Childrens Medical Center, Shanghai Jiaotong University Department of Electronic Engineering, Fudan University, Shanghai 200433, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）