The simulation of mechanical states of repaired articular cartilage
Though cartilage tissue is susceptible to damage anddifficult to self-repair, cartilage tissue engineering provides anideal way for the treatment of cartilage defects. Mechanicalenvironments have significant effects on the growth anddevelopment of cartilage. The research of mechanical states ofrepaired articular cartilage by tissue engineering hassignificantly clinical value. According to the physical structureand movement modes of the knee, a model for the treatment ofcartilage defects by tissue engineering was established based on the finite element method, with a rolling depression load as themechanical condition. Defect models of articular cartilage wererepresented by three different indicators: defect width, depth and the elastic modulus of artificial cartilage implanted. By finiteelement simulating, we theoretically studied the mechanical statesof articular cartilage repaired by tissue engineering. The resultsshow that the mechanical states varied in different parts of thedefect, and some stresses in the tissue engineered cartilage or hostcartilage deviated obviously from normally physiologicalconditions of the knee. An artificial cartilage with certainmechanical properties may contribute to the repair of cartilagedefects by tissue engineering.
Shuqing Zhang Minoru Mori Tetsuo Tsukahara Chunqiu Zhang Kazuhiko Shinozawa Lilan Gao Norihiro Hagita Minglin Sun Michiko Furutani Qiang Xu Yoshiyuki Furutani Rumiko Matsuoka
TianJin University of Technology, School of Mechanical Engineering, Tianjin Key Laboratory for Contr IREIIMS, Tokyo Womens Medical University, Tokyo, Japan ATR Intelligent Robotics and Communication L IREIIMS, Tokyo Womens Medical University, Tokyo, Japan The Hospital of Medical College of CPLAAP TIANJIN, CHINA
国际会议
成都
英文
1-4
2010-06-18(万方平台首次上网日期,不代表论文的发表时间)