A combining technique consisted of nano-TiO2 Photodynamic, immunity and electroporation methods for photokilling LoVo cancer cells, and inhibiting the growth of LoVo tumor

摘要：

An advance technique combined nano-TiO2 photodynamic with immunity and electroporation methods performs high efficiency for photokilling LoVo cancer cells even at very low concentration (3.12 μg/ml). The results showed that LoVo cells could be killed completely within 30 min using this method. The mechanism of this process was investigated using confocal florescent microscopy, TEM and comet assay methods. Few animal experimental results showed that this combining technique has the ability to inhibit the growth of LoVo tumor of nude mouse. There is a possibility to develop further this combinnng method as an efficient photodynamic therapy technique.

作者: Zhiyu Jiang Juan Xua Yi Suna Yan Jiang Wenliang Miao Hao wang

作者单位: Department of Chemistry, Fudan University,Shanghai， 200433, China Department of Biology, Fudan University, Shanghai， 200433, China Everong Biotechnics Co, Hangzhou， 310014，China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-5

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）