Parietal activity in labile and stabilized memory of Boolean rules

摘要：

Using event-related functional magnetic resonance imaging (fMRI) and the Ebbinghaus paradigm, we investigated the effect of memory in parietal cortex activity. In the course of one week, participants learned Boolean arithmetic tasks and were asked to master them perfectly. We measured cerebral activation with fMRI while healthy volunteers had learned and practiced Boolean rules on day 1 (i.e., labile memory condition) and day 7 (i.e., stabilized condition). A network of cortical areas was found to be differently activated during retrieval of labile and stabilized memory, including the left superior parietal lobule and precuneus for labile memory and the left inferior parietal lobule and postcentral gyrus for labile and stabilized memory. These results show that statespecific cortical networks are systematically activated during memory retrieval. We propose that memory stability following the automatic retrieval of rules involves information clustering across time and, simultaneously, to process the repetitive Boolean problems with minimal resources by mediation of parietal areas.

作者: Xiuzhen Wang Ning Zhong Shengfu Lu Weiquan Gu Hongxia Wang

作者单位: Learning & cognition Lab, The International WIC Institute, Beijing University of Technology, Beijing The International WIC Institute, Beijing University of Technology, Beijing 100022, China Department The International WIC Institute, Beijing University of Technology, Beijing 100022, China Harbin Normal University, Harbin 150301, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）