会议专题

Dose-response function of an amorphous silicon electronic portal imaging device

Electronic Portal Imaging Devices (EPID) are not only suited for patient set-up verification and detection of organ motion but can also be used for dosimetric verification of treatment techniques or in-vivo dosimetry. The aim of this work is to develop a mapping function which describes the relationship between the pixel value and exit dose of an amorphous silicon (a-Si) EPID. The dose-response function depends on field size, source-detector distance (SDD) and the monitor unit (MU) setting. To experimentally derive the coefficients, EPID data and ionization chamber in a mini-phantom, which are used as reference data, were fit and compared on the central axis for detector distances between 105cm to 125cm from the source, radiation field sizes from 5cm×5cm to 15cm×15cm and monitor unit settings of 50,100,150.All measurements were done using 6 MV photon beams at a Varian Clinac 23EX medical accelerator equipped with the Varian aS1000 a-Si EPID system. Each dose profile was evaluated by comparing the EPID with the ionization chamber measurement. The comparisons indicate a maximum deviation was < 6%. It is found that accuracies of better than 1% could be obtained if field size ≥10cm×10cm, because the effect of the lateral scatter was bigger in small field size. It is concluded that, using our model, EPID measurements can be used to estimate accurate two-dimensional dose distribution in a 6MV beam with 300MU/min.

Wenting Lu Linghong Zhou Jun Yang Xin Zhen

School of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China

国际会议

The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

成都

英文

1-4

2010-06-18(万方平台首次上网日期,不代表论文的发表时间)