The pilot study of phthalates and monoesters in human chorion tissues
Phthalates are widely used in industry as solvents, additives and plasticizers. Some phthalates and their monoester metabolites are known to cause carcinogenic, toxic or endocrine-modulating effects. Chorion tissues as human early embryo are the base of organogenesis. Embryo (3-8 weeks) is sensitive period of teratogensis. With the development of industrialization, in addition to genetic factors, environmental factors become an important reason for human reproductive system defect, particularly under the interaction of the environmental factors and genetic factors. Recently we have studied human chorion tissues to see whether the phthalates especially their monoester metabolites are exist in. In the result five phthalates and monoester metabolites such as dibutyl phthalate (DBP), butyl benzyl phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), monobutyl phthalate(MBP) and mono(2-ethyl-hexyl) phthalate(MEHP) are discovered, that means that phthalates and their monoesters both can pass through embryo and affect fetus before birth.
yahui Zhao xiaohui Cai cheng Shi hong Kang xiaoyi Wang xingtao Lin jingqiang Zhao huiming Ke hairong Ren qun Lu huan Shen hongjing Han
College of Environment and Energy Engineering beijing univ.of technol.beijing,china Family Planning and Reproductive Medicine Center Peoples Hospital of Beijing University beijing,chi
国际会议
成都
英文
1-3
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）