Optimization of the operational parameters for oestrone quantification in sewage and river water matrices using response surface method

摘要：

Response surface method (RSM) is a set of mathematical and statistical methods for experimental design and evaluating the effects of variables and searching optimum conditions of variables topredict targeted responses. Oestrone (E1) is one of the most important steroid estrogens in sewage and waterbody. An internal standard method of HPLC-MS-MS for E1 is established with its operational parameters in the multiple reaction monitoring (MRM) mode being optimized by RSM. With a sample pretreatment using two-step solid phase extraction (SPE), the detection limit of the method was 0.5 ng/L.

作者: Wan Qiaoling Yang Chun Zhang Zhi Lian Peng

作者单位: Key Laboratory of Three Gorges Reservoir Regions Eco-Environment under Ministry of Education, Chongqing University, Chongqing, China

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）