Acute toxicity and mutagenicity of extract from Eriobotrta japonica
To study the acute toxicity and the mutagenicity of Eriobotrya japonica extract. The oral acute toxicity test in mice Ames test , micronucleus test in bone marrow and sperm abnormality test were carried out. The reults shown that tolerated dose of 20g/kg body weight in mice could be regarded as virtually non-toxic. The micronucleus rates and sperm abnormality rates in all doses were not significantly different from the control group. No increase in the number of revertant colonies was found in the Ames test with and without S9 mixture.So acute toxicity and the mutagenicity of Eriobotrya japonica extract were not observed in this study.
Xueyuan Jin Haili Dong
Department of Chemistry Engineering Huainan Union University Huainan,China
国际会议
成都
英文
1-3
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）