Fabrication, surface properties and protein encapsulation/release studies of electrospun gelatin nanofibers
The composite nanofibrous mats electrospun from a solution consisting of gelatin, Bovine Serum Albumin (BSA, a model compound to simulate proteins), Polyethylene glycol sorbitan monolaurate (Tween-20) and 2,2,2-trifluoroethanol (TFE) was prepared and characterized. The morphologies of the nanofibrous mats were examined by scanning electron microscopy (SEM); the surface hydrophilicity was measured by the water contact angle method; and the protein release profiles from the electrospun nanofibrous mats immersed in phosphate buffered saline (PBS) for various time periods were recorded and analyzed. The results indicated that the composite nanofibrous mat electrospun from the emulsion had the most desired and controllable protein release behaviours and it could be utilized as both a drug/protein encapsulation vehicle and a tissue engineering scaffold.
LI Xiaoqiang SU Yan MO Xiumei
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University,S State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University,
国际会议
2009 International Conference on Advanced Fibers and Polymer Materials(2009年先进纤维与聚合物材料国际学术会议)
上海
英文
24-26
2009-10-21（万方平台首次上网日期，不代表论文的发表时间）