Prolonged and sustained drug delivery behavior of poly(N-isopropylacrylamide)/clay/linear polyacrylamide hydrogels

摘要：

In this contribution, a novel smart drug delivery system (DDS) based on poly(N-isopropylacrylamide) (PNIPAAm), clay and linear polyacrylamide (PAAmhydrogel was developed for prolonged and sustained controlled drug release. Various amounts linear PAAm were incorporated into poly(N-isopropylacrylamide)/clay (PNIPAAm) hydrogels to form the novel DDSs. Bovine serum albumin (BSA) was used as model drug for in vitro experiment, the release data suggested that the controlled drug release could be achieved by modulating linear PAAm content.

作者: JIANG Yongmei ZHANG Gaoqi YU Hao LI Biao WU Yongtao ZHU Meifang

作者单位: State Key Lab.For Modification of Chemical Fibers & Polymer Materials, College of Material Science Zhejiang Chuanhua Corporation Limited, North End of Tonghui Road., Economic And Technical Develop State Key Lab.for Modification of Chemical Fibers & Polymer Materials, College of Material Science

会议类型: 国际会议

会议名称: 2009 International Conference on Advanced Fibers and Polymer Materials(2009年先进纤维与聚合物材料国际学术会议)

会议地点: 上海

会议语种:英文

页码: 1270-1273

在线出版日期: 2009-10-21（万方平台首次上网日期，不代表论文的发表时间）