Electrospun bioactive composite scaffolds of hydroxyapatite /poly( ε-caprolactone) for bone tissue engineering

摘要：

Hydroxyapatite (HA)/poly(ε-caprolactone) (PCL) fibrous scaffolds were successfully prepared by electrospinning dopes containing HA and PCL in mixed solvents of methylene chloride and N, N-dimethyl formamide (MC/DMF). The scaffolds were characterized by SEM, TEM, tensile strength tests and in-vitro bioactivity tests. It was found that surface modification of HA with γ-glycioxypropyl-trimethoxysilane (A-187) could improve mechanical performance and bioactivity of PCL fibrous scaffolds greatly.

作者: LI Lingli LI Guang JIANG Jianming

作者单位: Eye Hospital, School of Optometry & Opthalmology, Wenzhou Medical College, 270 Xueyuan Road,Wenzhou State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua Universi

会议类型: 国际会议

会议名称: 2009 International Conference on Advanced Fibers and Polymer Materials(2009年先进纤维与聚合物材料国际学术会议)

会议地点: 上海

会议语种:英文

页码: 1291-1294

在线出版日期: 2009-10-21（万方平台首次上网日期，不代表论文的发表时间）