Genetic influences on pubertal development and endrocrine regulators in females
Introduction Genetic and environmental effects on pubertal development are likely to be mediated through influence on pubertal regulators. The Somatometer hypothesis proposed that factors that regulate or emanate from the rapid increments in body compositions at the transition to puberty might be important in regulating the onset of puberty. Two such growth-derived signals, leptin and insulin-like growth factor 1 (IGF-1), are leading candidates linking peripheral energy status to the hypothalamus to regulate the developmental increase in gonadotropin-releasing hormone (GnRH) secretion and are involved in the pubertal development and metabolic disorders.
Li Hong-juan Ji Cheng-ye
Beijing Sport University, China Peking University, China
国际会议
广州
英文
212-213
2008-08-01（万方平台首次上网日期，不代表论文的发表时间）