PPAR-y gene polymorphism is associated with exercise-mediated changes of serum c-reactive protein in healthy men
Introduction Insulin resistance is a key factor in the pathogenesis of type 2 diabetes. Cross-sectional and retrospective epidemiological studies have provided direct evidence that a lack of physical activity is strongly associated with type 2 diabetes, and physical inactivity is an independent risk factor for insulin resistance and type 2 diabetes. Moderate-tovigorous leisure-time physical activity protects against the development of type 2 diabetes. PPARy, a nuclear receptor that regulates genes involved in lipid and glucose metabolism, contributes to the onset of diabetes. Recently, it has been reported that PPARy gene polymorphism correlated with the improved insulin resistance after exercise in healthy Japanese men.
Wang Yu
Department of Sports Medicine of Chengdu Sport University, China
国际会议
广州
英文
931-932
2008-08-01（万方平台首次上网日期，不代表论文的发表时间）