Development of CFTR activators from Chinese medicinal plants to improve pulmonary adaptation to altitude/hypoxia stress

摘要：

Introduction CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) is a chloride channel on the airway epithelia, playing a major role in electrolyte and fluid transport. It is well documented that cystic fibrosis, the most common genetic respiratory disease, is caused by mutations in the CFTR gene that lead to dysfunction and/or improper localization of the protein. Approximately one in every 25 Caucasians carries one mutant version of this gene as a heterozygote.

作者: Li Canhui Viirre Russell Marshall John

作者单位: The Hospital for Sick Children in Toronto, Canada Ryerson University, Canada Ryerson University, Canada

会议类型: 国际会议

会议名称: 2008年奥林匹克科学大会

会议地点: 广州

会议语种:英文

页码: 995-996

在线出版日期: 2008-08-01（万方平台首次上网日期，不代表论文的发表时间）