Preparation of Silica Gel Grafting Bisquarternary Phosphonium and Its Antibacterial Activities Studies
Using the activate silica gel as a carrier reacted with (3-Chloropropyl) trimethoxy silane, the product was early or late reacted with 1,3-Bis(diphenylphosphino)propane,1-chlorotetradecane to give the bisquarternary phosphonium salt water-insoluble antibacterial material. The effect of the reaction temperature, the reaction time and the reaction solvent were studied by means of the orthogonal design method and the single-factor experiment. The optimum conditions are: reaction temperature 150℃, reaction time 48h and the reaction solvent is ortho dichlorobenzene. The product has grafted with 0.68 mmol/g phosphonium group and 0.15 mmol/g long alkyl. 1,3-Bis(diphenylphosphino)propane and 1-chlorotetradecane have been early or late grafted to silica gel, characterized by FTIR and TG. The bactericidal rate of the bactericide material was up to 99.9％ at the using amount of 20mg /mL in 45min. The antimicrobial activity of the bactericidal material is still up to 98.7％, after 5 times repeated usage.
silica gel bisquarternary phosphonium water-insoluble antibacterial material
FU Shi-Hai ZHANG Fan JING Dong LU Xiao-Ping HAN Ping-fang
College of Chemistry and Chemical Technology, Nanjing University of Technology,Nanjing 210009, Jiangsu, China
国际会议
北京
英文
166-173
2010-05-17（万方平台首次上网日期，不代表论文的发表时间）