In vivo photoacoustic imaging of osteosarcoma on animal model

摘要：

Osteosarcoma is the commonest primary malignant tumor of bone, and the second highest cause of cancerrelated death in the paediatric age group. Although there are several methods for osteosarcoma detection, e.g. X-ray, CT, MRI and bone scan, they are not satisfied methods because they can hardly detect osteosarcoma in early stage. Photoacoustic imaging (PAI) is an emerging hybrid imaging modality that is noninvasive, nonionizing, with high sensitivity, satisfactory imaging depth and good temporal and spatial resolution. In order to explore this new method to detect osteosarcoma, we established SD rat models with osteosarcoma and utilized PAI to reconstruct the osteosarcoma image in vivo. This is the first time detecting osteosarcoma in vivo using PAI, and the results suggested that PAI has potential clinical application for detecting osteosarcoma in the early stage.

作者: Menglei Yu Fei Ye Jun Hu

作者单位: Department of Orthopaedics, The First Affiliated Hospital, Shantou University Medical Coltege, Shant MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of iophotonics,

会议类型: 国际会议

会议名称: The 9th International Conference on Photonics and Imaging in Biology and Medicine(第九届生物医学光子学与成像技术国际学术研讨会 PIBM 2010)

会议地点: 武汉

会议语种:英文

页码: 1-7

在线出版日期: 2010-11-02（万方平台首次上网日期，不代表论文的发表时间）