A New Type of Colored Alumina/glass Composite Biological Safety Assessment - Cell Toxicity and Hemolysis Tests
Objective: to evaluate the biological safety of a colored alumina/glass composite in terms of cytotoxicity and hemolytic ability. Methods: the cytotoxicity of an alumina/glass composite was evaluated with molecular filtration method. Cytotoxicity by spectrophotometric responses of test material and responses of a fresh rabbit red blood anticoagulant solution was determined by spectrophotometer. Results: cell-coated filter paper in contact with the test material showed the appearance of intracellular blue dye as the same staining density as in control samples,leading to a toxicity rating of 0. Colored alumina/glass composite assayed at <5％ hemolysis. Conclusion: colored alumina/glass composite materials showed low cytotoxicity and non-acute hemolytic rates,representing overall good biological safety under these conditions.
Alumina/glass composite Hemolysis test Cell toxicity test
Bin Deng Huai-Xiu Lu Long-quan Shao Yuan-Fu Yi Jie Liu Kang-Lin Hou Wei-Wei Zhang Ning Wen
Department of Stomatology,Chinese PLA General Hospital,Beijing 100853,China Department of Stomatology,Navy General Hospital,Beijing 100048,China Department of Stomatology, Nanfang Hospital of Southem Medical University,Guangzhou 510515,China Department of Stomatology,General Hospital of Armed Police Forces,Beijing 100039, China
国际会议
Frist Annual Meeting on Testing and Evaluation of Inorganic Materials(第一届全国无机材料测试与评价学术年会)
南昌
英文
459-461
2010-04-28（万方平台首次上网日期，不代表论文的发表时间）