STUDY ON THE SYNTHESIS AND SELF-ASSEMBLY BEHAVIOR OF HYDROPHOBICALLY MODIFIED HYDROXYETHYL CELLULOSE

摘要：

In this paper, hydrophobically modified hydroxyethyl cellulose (HMHEC) was synthesized by the etherificaiton reaction between hydroxyethyl cellulose (HEC) and long chain alkyl bromide. The structure of products was characterized by FT-IR, 1HNMR and viscosimeter, and their self-assembly behavior was observed by the atom force microscope (AFM) and dynamic laser scattering (DLS). The results of FT-IR and 1H-NMR showed that the hydrophobically hydroxyethyl cellulose (HMHEC) was successfully synthesized. In comparison with HEC, the viscosity of hydrophobically modified derivatives was obviously increased. The results of AFM and DLS analysis indicated that the hydrophobically hydroxyethyl cellulose was able to self-assemble in water and form into nano-sized polymeric micelles that are ideal for carrying water-insoluble drugs and functional compounds.

关键词： hydroxyethyl cellulose alkyl bromide hydrophobic modification self-assembly activity

作者: Yanzhu Guo Dong Li Xiaohui Wang Runcang Sun

作者单位: State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou

会议类型: 国际会议

会议名称: 16th International Symposium on Wood,Fiber and Pulping Chemistry(第十六届木材、纤维及制浆化学国际会议)

会议地点: 天津

会议语种:英文

页码: 432-435

在线出版日期: 2011-06-08（万方平台首次上网日期，不代表论文的发表时间）