An Iterative Strategy for Bi-objective Optimization of Metabolic Pathways

摘要：

This paper proposes an iterative strategy to address the bi-objective optimization of metabolic pathways.The metabolic system is firstly represented by the Ssystem formalism.Then a weighted-sum method is used iteratively to maximize the performance of a metabolic pathway while minimizing its cost.The presented iterative strategy is applied to the fermentation pathway in Saccharomyces cerevisiae and shown to the effectiveness of the approach.

关键词： metabollc pathways bi-objective optimization weighted-sum method

作者: Gongxian Xu

作者单位: Department of Mathematics Bohai University Jinzhou,China

会议类型: 国际会议

会议名称: The Fourth International Joint Conference on Computational Science and Optimization(第四届计算科学与优化国际大会 CSO 2011)

会议地点: 昆明、丽江

会议语种:英文

页码: 587-588

在线出版日期: 2011-04-15（万方平台首次上网日期，不代表论文的发表时间）