Complexation of Synthetic and Natural Insecticides by Cyclodextrins for Both Safe Application and Controlled Release
Cyclodextrins are known to form complexes with hydrophobic compounds, e.g. with insecticides. In this work, a series of different synthetic and natural active agents which are used especially for insect-proofing of wool textiles were selected for theoretical and preparative studies on their complexation by β-cyclodextrin. The energetically preferred β-cyclodextrin complexes of the selected ingredients were calculated by computer based Monte Carlo force field simulations. The resulting ranking list with the theoretically most stable β-cyclodextrin insecticide complexes is presented. It shows that greater molecules form less stable complexes with β-cyclodextrin than suitable smaller molecules. Based on these calculations, β-cyclodextrin insecticide complexes were prepared and characterized by different analytical methods. Studies by head space GC/MS analysis show that the release process depends on the guest molecule and on the present water content.
cyclodextrins complexation insecticides controlled release molecular modeling
KETTEL Markus J. SCHAEFER Karola KOERNER Andrea BEGINN Uwe MOELLER Martin
DWI an der RWTH Aachen e.V.and Institute of Technical and Macromolecular Chemistry,RWTH Aachen Unive Institute for Chemistry, University of Osnabrueck, 49076 Osnabrueck, Germany
国际会议
The 12th International Wool Research Conference(第十二届国际羊毛会议12th IWRC)
上海
英文
198-202
2010-10-19（万方平台首次上网日期，不代表论文的发表时间）