TAILOR-MADE COPOLYMERS FOR RESPONSIVE DRUG DELIVERY NANOSYSTEMS

摘要：

Amphiphilic macromolecules combining a biodegradable and a bioeliminable block have been synthesized in order to build micellar drug delivery systems. Particularly, redox reversible disulfide linkages have been introduced in the structure to ensure cross-linking of the micelles formed in water and prevent their dissociation at high dilution upon injection. The synthesis of polymers and their micellization will be especially emphasized in this paper.

关键词： biomaterials polymer micelles cross-linked micelles glutathione responsive micelles

作者: Sebastien Cajot Christine Jerome

作者单位: Center for Education and Research on Macromolecules (CERM), University of Liege, B6 Sart tilman,B-4000 Liege, Belgium

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 63-65

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）