AMINO ACID BASED POLYESTERAMIDES AND POLYESTERURETHANES:CELL RESPONSIVE MATRICES FOR DRUG DELIVERY

摘要：

The incorporation of amino acid-based building blocks in polyesteramides or polyurethanes offers more than providing metabolizable building blocks. They provide one or more reactive sites that allow further modification of the polymer to tailor physicochemical properties, tune cellular response and degradation that can be either hydrolytic or enzymatic. In this paper we will utilise amino acid based polyesteramides (1) and polyesterurethanes (2) to exemplify various aspects raised by the use of amino acid based degradable polymers and their consequences on degradation and controlled release.

关键词： synthesis lysine enzymatic degradation fibroblasts coatings

作者: Aylvin A.Dias Bart.Plum G.Mihov Bill Turnell

作者单位: DSM Biomedical, Koestraat 1, Geleen 6167 RA, The Netherlands

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 81-83

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）