CONTROLLED HEPARIN RELEASE FROM ELECTROSPUN GELATIN FIBERS

摘要：

Heparin was incorporated into electrospun gelatin fibers to improve their hemocompatibility. The uniform nanofibers without beads could be manufactured by electrospinning technology from 18 wt.％ gelatin-acetic acid solution with 0.18 wt.％ and 0.90 wt.％ heparin. The fiber diameters decreased significantly compared with the fibers without heparin. Approximate 33％ of the encapsulated heparin was released by diffusion from the heparin/gelatin nanofibers in 14 days.

关键词： electrospinning release cross-linking gelatin heparin

作者: Heyun Wang Yakai Feng Haiyang Zhao Jian Lu Jintang Guo Marc Behl Andreas Lendlein

作者单位: School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China,Tianjin Uni Tianjin University-GKSS Research Centre, Joint Laboratory for Biomaterials and Regenerative Medicine

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 118-120

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）