SYNTHESIS OF AMPHIPHILIC HYPERBRANCHED POLYMERS FOR THE CONTROLLED RELEASE OF DOUBLE-GUEST MOLECULES

摘要：

In order to achieve a controlled release of double-guest molecules, an amphiphilic hyperbranched polymer consisting of a hydrophobic hyperbranched poly(β-cyclodextrin) core and a hydrophilic methoxy polyethylene glycol shell was first synthesized via click chemistry between azido groups and alkynyl groups. Then the controlled release behavior of this polymer with respect to double-guest molecules including Levofloxacin lactate and Rhodamine B was studied by UV. The results showed that controlled release of double-guest molecules using the novel polymer carrier can be achieved.

关键词： amphiphilic hyperbranched polymer click chemistry double-guest molecules controlled release behavior

作者: Wei Tian Xiaoying Wei Guang Yang Xiaodong Fan

作者单位: Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xian 710072, China

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 255-257

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）