MONODISPERSE PLA/PLGA NANOPARTICLES FABRICATION THROUGH A SURFACTANT-FREE ROUTE

摘要：

Polymer nanoparticles are extensively researched for applications in drug and vaccine delivery. Here, we report the preparation of monodisperse PLA/PLGA nanoparticles through a self-organized precipitation route. Sizes of the nanoparticles can be tuned through changing the initial polymer concentration, organic solvent/water ratio or solvent evaporation rate. Drugs or semiconductor nanoparticles can be encapsulated into these polymer nanoparticles.

关键词： polymer nanoparticles size-controllable biodegradation monodisperse

作者: Ruijing Liang Jintao Zhu

作者单位: Institute of Polymer Science and Engineering, School of Chemistry and Chemical Engineering,Huazhong University of Science and Technology, Wuhan 430074, China

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 321-323

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）