SUICIDAL GENE THERAPY AGAINST TUMOR USING REDUCIBLE POLY (OLIGO-D-ARGININE)

摘要：

Reducible poly(oligo-D-arginine) (rPOA) is a promising non-viral gene delivery carrier, providing lower cytotoxicity and higher gene expression efficiency compare to PEL rPOA showed a higher level of HSV-TK gene expression in comparison with PEI in brain tumor cells and subsequently induced high cytotoxicity on tumor cells, in the presence of ganciclovir (GCV).

关键词： suicide gene therapy HSV-TK ganciclovir non-viral gene carrier

作者: Kyung-Min Kim Young-Wook Won Partho Protim Adhikary Yun-Mi Hwang Yong-Hee Kim

作者单位: Department of Bioengineering, Institute for Bioengineering and Biopharmaceutical Research,Hanyang Un Department of Bioengineering, Institute for Bioengineering and Biopharmaceutical Research,Hanyang Un

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 357-359

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）