COMPOSITE FIBROUS MATRICES PREPARED BY ELECTROSPINNING WITH VARIOUS VOLUMES TO CONTROL THE AMOUNT OF IMMOBILIZED BASIC FIBROBLAST GROWTH FACTORS AND ITS IN VITRO BIOACTIVITY

摘要：

We fabricated composite fibrous matrices with various volumes, ultimately to control the amount of immobilized basic fibroblast growth factor (bFGF). The fibrous matrices appeared to have an open-porous structure and the amount of bFGF on fibrous matrices was increased with increasing the volumes of matrices. Controlled release of bFGF from the matrices was achieved for 56 days. During in vitro test, the released bFGF maintained its bioactivity and enhanced proliferation of human mesenchymal stem cells.

关键词： electrospinning heparin basic fibroblast growth factors human mesenchymal stem cells

作者: Min Sup Kim Ji-hye Lee Seok Joo Kim Heungsoo Shin

作者单位: Department of Biomedical Engineering,Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133- Department of Bioengineering,Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Kor Department of Bioengineering,Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Kor

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 360-362

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）