CONTROLLED RELEASE OF BOVINE SERUM ALBUMIN FROM ELECTROSPUN FIBROUS MEMBRANES VIA AN IMPROVED EMULSION-CORE TECHNIQUE

摘要：

Bovine serum albumin (BSA), entrapped in a water-in-oil emulsion as the core, was encapsulated in the shell polymer via emulsion-core (EC) coaxial electrospinning. Fibrous membranes prepared via this improved electrospinning technique could successfully reduce the initial release of BSA. Additionally, the release rate could be tailored by changing the composition of poly(L-lactide-co-glycolide) in the core emulsion. The results showed that EC coaxial electrospinning performed better than conventional coaxial electrospinning with respect to protein delivery in tissue engineering.

关键词： emulsion-core coaxial electrospinning bovine serum albumin poly(L-lactide-co-glycolide) controlled release

作者: Hong Zhang Yunhui Zhao Fengxuan Han Min Wang Xiaovan Yuan

作者单位: School of Materials Science and Engineering, and Tianjin Key Laboratory of Composite and Functional Department of Mechanical Engineering, The University of Hong Kong, Hong Kong,China

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 422-424

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）