NANOPATTERNED 3D STRUCTURE FOR GUIDANCE OF CELLS

摘要：

Nanopatterned biodegradable polymer substrates are prepared by a nano-imprinting technique. Fibroblasts are used as model cells and cultured on the grooved surface to determine the cell behavior. The orientation and morphology of the cells indicate their response to surface nano-topographies and polarization along the length axis. Nanoscale surface features can direct cellular functions such as activation, orientation, and migration. These phenomena are of interest for understanding cytoskeleton dynamics and designing biomaterials for 3D axon guidance.

关键词： cell behavior nano-topography patterning polymer

作者: Xiaoyi Xu Byung-Yeon Choi Kyung-Tai Kim Giyong Tae Gun-young Jung Mi-Ryoung Song Young Ha Kim

作者单位: Cancer Center, First Hospital, Jilin University, 71 Xinmin Street, Changchun 130021, China,Gwangju I Gwangju Institute of Science and Technology (GIST), 261 Cheomdan-gwagiro (Oryong-dong), Buk-gu, Gwan

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 558-560

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）