VERSATILE SYNTHESIS OF FUNCTIONAL BIODEGRADABLE POLYMERS BY RING-OPENING POLYMERIZATION AND MICROWAVE-ASSISTED CLICK REACTION

摘要：

Pendant azido functionalized cyclic carbonate monomer, 2,2-diazidomethyltrimethylene carbonate (DATC) was prepared and its copolymers with LA were synthesized by ring-opening polymerization (ROP). The azido groups were capable of click reactions with various alkyne-containing molecules such as propargyl alcohol, propynylamine, 4-pentynoic acid, alkyne-terminated mPEG and alkyne-terminated poly(N-isopropylacrylamide) under microwave-assisted conditions. These functionalized polyesters have potential applications in drug delivery.

关键词： cyclic carbonate ROP microwave-assisted click reaction graft copolymer

作者: Lesan Yan Jianxun Ding Ruogu Qi Lixin Yang Xiuli Hu Yubin Huang Xiabin Jing

作者单位: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry,Chin State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry,Chin

会议类型: 国际会议

会议名称: The First Symposium on Innovative Polymers for Controlled Delivery(新型高分子材料与控制释放国际会议 SIPCD 2010)

会议地点: 苏州

会议语种:英文

页码: 561-563

在线出版日期: 2010-09-14（万方平台首次上网日期，不代表论文的发表时间）