Cortical Sulcal Atlas Construction Using a Diffeomorphic Mapping Approach

We present a geometric approach for constructing shape atlases of sulcal curves on the human cortex. Sulci and gyri are represented as continuous open curves in R3, and their shapes are studied as elements of an infinite-dimensional sphere. This shape manifold has some nice properties – it is equipped with a Riemannian L2 metric on the tangent space and facilitates computational analyses and correspondences between sulcal shapes. Sulcal mapping is achieved by computing geodesics in the quotient space of shapes modulo rigid rotations and reparameterizations. The resulting sulcal shape atlas is shown to preserve important local geometry inherently present in the sample population. This is demonstrated in our experimental results for deep brain sulci, where we integrate the elastic shape model into surface registration framework for a population of 69 healthy young adult subjects
Shantanu H.Joshi ArthurW.Toga Ryan P.Cabeen Bo Sun Anand A.Joshi Boris Gutman Alen Zamanyan Shruthi Chakrapani Ivo Dinov Roger P.Woods
Laboratory of Neuro Imaging, University of California, Los Angeles CA 90095, USA Research Center for Sectional and Imaging Anatomy, Shandong University School ofMedicine, 44 Wenhua
国际会议
北京
英文
357-366
2010-09-01(万方平台首次上网日期,不代表论文的发表时间)