Model-Free and Analytical EAP Reconstruction via Spherical Polar Fourier Di..usion MRI
How to estimate the di..usion Ensemble Average Propagator (EAP) from the DWI signals in q-space is an open problem in di..usion MRI field. Many methods were proposed to estimate the Orientation Distribution Function (ODF) that is used to describe the fiber direction. However, ODF is just one of the features of the EAP. Compared with ODF, EAP has the full information about the di..usion process which reflects the complex tissue micro-structure. Di..usion Orientation Transform (DOT) and Di..usion Spectrum Imaging (DSI) are two important methods to estimate the EAP from the signal. However, DOT is based on mono-exponential assumption and DSI needs a lot of samplings and very large b values. In this paper, we propose Spherical Polar Fourier Imaging (SPFI), a novel model-free fast robust analytical EAP reconstruction method, which almost does not need any assumption of data and does not need too many samplings. SPFI naturally combines the DWI signals with di..erent b-values. It is an analytical linear transformation from the q-space signal to the EAP profile represented by Spherical Harmonics (SH).We validated the proposed methods in synthetic data, phantom data and real data. It works well in all experiments, especially for the data with low SNR, low anisotropy, and non-exponential decay
Jian Cheng Aurobrata Ghosh Tianzi Jiang Rachid Deriche
Athena Project Team, INRIA Sophia Antipolis – Mediterranee, FranceCenter for Computational Medicine, Athena Project Team, INRIA Sophia Antipolis – Mediterranee, France Center for Computational Medicine, LIAMA, Institute of Automation,Chinese Academy of Sciences, China
国际会议
北京
英文
590-597
2010-09-01（万方平台首次上网日期，不代表论文的发表时间）