Temporal Diffeomorphic Free-Form Deformation for Strain Quantification in 3D-US Images
This paper presents a new diffeomorphic temporal registration algorithm and its application to motion and strain quantification from a temporal sequence of 3D images. The displacement field is computed by forward eulerian integration of a non-stationary velocity field. The originality of our approach resides in enforcing time consistency by representing the velocity field as a sum of continuous spatiotemporal BSpline kernels. The accuracy of the developed diffeomorphic technique was first compared to a simple pairwise strategy on synthetic US images with known ground truth motion and with several noise levels, being the proposed algorithm more robust to noise than the pairwise case. Our algorithm was then applied to a database of cardiac 3D+t Ultrasound (US) images of the left ventricle acquired from eight healthy volunteers and three Cardiac Resynchronization Therapy (CRT) patients. On healthy cases, the measured regional strain curves provided uniform strain patterns over all myocardial segments in accordance with clinical literature. On CRT patients, the obtained normalization of the strain pattern after CRT agreed with clinical outcome for the three cases.
Mathieu De Craene Marta Sitges Alejandro F.Frangi Gemma Piella Nicolas Duchateau Etel Silva Adelina Doltra Hang Gao Jan D’hooge Oscar Camara Josep Brugada
Information and Communication Technologies Department,Universitat Pompeu Fabra, Barcelona, Spain Net Hospital Clinic; IDIBAPS; Universitat de Barcelona, Spain Information and Communication Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain Ne Department of Cardiovascular Diseases, Cardiovascular Imaging and Dynamics,Katholieke Universiteit L
国际会议
北京
英文
1-8
2010-09-01（万方平台首次上网日期，不代表论文的发表时间）