3D Localization of Pronuclei of Human Zygotes Using Textures from Multiple Focal Planes

摘要：

We propose a technique for recovering the position and depth of pronuclei of human zygotes, from Z-stacks acquired using Hoffman Modulation Contrast microscopy. We use Local Binary Pattern features for describing local texture, and integrate information from multiple neighboring areas of the stack, including those where the object to be detected would appear defocused; interestingly, such defocused areas provide very discriminative information for detection. Experimental results confirm the effectiveness of our approach, which allows one to derive new 3D measurements for improved scoring of zygotes during In Vitro Fertilization.

作者: A.Giusti G.Corani L.Gambardella C.Magli L.Gianaroli

作者单位: Dalle Molle Institute for Artificial Intelligence (IDSIA), Lugano, Switzerland International Institute for Reproductive Medicine (IIRM), Lugano, Switzerland INFERGEN, Lugano, Switzerland

会议类型: 国际会议

会议名称: The 13th International Conference on Medical Image Computing and Computer-Assisted Intervention(第13届医学影像计算与计算机辅助介入国际会议 MICCAI 2010)

会议地点: 北京

会议语种:英文

页码: 488-495

在线出版日期: 2010-09-01（万方平台首次上网日期，不代表论文的发表时间）