Model-Based Multi-view Fusion of Cinematic Flow and Optical Imaging

摘要：

Bioluminescence imaging (BLI) offers the possibility to study and image biology at molecular scale in small animals with applications in oncology or gene expression studies. Here we present a novel modelbased approach to 3D animal tracking from monocular video which allows the quantification of bioluminescence signal on freely moving animals. The 3D animal pose and the illumination are dynamically estimated through minimization of an objective function with constraints on the bioluminescence signal position. Derived from an inverse problem formulation, the objective function enables explicit use of temporal continuity and shading information, while handling important self-occlusions and time-varying illumination. In this model-based framework, we include a constraint on the 3D position of bioluminescence signal to enforce tracking of the biologically produced signal. The minimization is done efficiently using a quasi-Newton method, with a rigorous derivation of the objective function gradient. Promising experimental results demonstrate the potentials of our approach for 3D accurate measurement with freely moving animal.

作者: Mickael Savinaud Martin de La Gorce Serge Maitrejean Nikos Paragios

作者单位: Laboratoire MAS, Ecole Centrale Paris, FranceEquipe GALEN, INRIA Saclay - Ile de France, Orsay, Fran Laboratoire MAS, Ecole Centrale Paris, France Biospace Lab, Paris, France Laboratoire MAS, Ecole Centrale Paris, France Equipe GALEN, INRIA Saclay - Ile de France, Orsay, Fra

会议类型: 国际会议

会议名称: The 13th International Conference on Medical Image Computing and Computer-Assisted Intervention(第13届医学影像计算与计算机辅助介入国际会议 MICCAI 2010)

会议地点: 北京

会议语种:英文

页码: 668-675

在线出版日期: 2010-09-01（万方平台首次上网日期，不代表论文的发表时间）