Application of Hierarchical Cluster Analysis in the Classification of Pentacyclic Triterpenoids and Their Salt Derivatives
Eight kinds of salt derivatives of triterpene acids were prepared. The cluster analysis was applied for the study of ursolic acid, oleanolic acid and 8 salt derivatives, according to the measured value of water-solubility and antibacterial activity. The results of cluster analysis showed that the ten compounds can be clustered into three groups approximately. Most of the compounds have great similarities in biological activity.
salt derivatives triterpene acid antibacterial activity cluster analysis
LI Suyun ZONG Wei ZHANG Hejun MIAO Rongchen
School of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou,P.R.China, 450002
国际会议
威海
英文
396-399
2010-07-24(万方平台首次上网日期,不代表论文的发表时间)