Preparation of Polymer/Clay Nanocomposite Hydrogel and Its Bio-application as Barrier Materials
A series of novel high clay content poly (Nisopropylacrylamide) (PNIPAAm), poly (lacrylamide) (PAAm) copolymer nanocomposite hydrogels (NC gels) have been successfully prepared by using Laponite XLS (Clay-S), a kind of synthetic hectorite modified by tetrasodium pyrophosphate (Na4P2O7) as crosslinker. The mechanical strength was investigated. The result revealed that the PNIPAAm-co-PAAm/clay hydrogels exhibit excellent mechanical properties and with increasing Clay-S content, the mechanical properties increase further. Bio-security tests of hypersensitivity, pyrogen, acute system toxicity, cytotoxicity were developed on the hydrogels. Test data were analyzed and evaluated as well. The results confirmed that PNIPAAm-co-PAAm/clay hydrogelss are of bio-security and suitable to be used as biomedical barrier materials.
clay nanocomposite hydrogels barrier materials
Jiang Yongmei Chen Minjie Liu Yang Yang Chi Zhu Meifang
State Key Lab for Modification of Chemical Fibers & Polymer Materials, College of Material Science a No.9 Peoples Hospital of Shanghai, 639 Zizhaoju Road, Shaghai 200011
国际会议
上海
英文
879-882
2009-05-27（万方平台首次上网日期，不代表论文的发表时间）