Prediction and Identification of B-Cell Epitopes on Goose Parvovirus Capsid Protein
The capsid protein (VP) gene of goose parvovirus (GPV) was translated into amino sequence by Editseq. The secondary structure and B-cell epitopes of the deduced protein were predicted by Protean. Combining the results according to these methods, the VP has complicated secondary structure. There are several potential B-cell epitopes on VP. By means of overlapping peptides expressed in Escherichia coli in combination with Western blotting, B-cell epitopes were identified on VP. The results show virtual linear immunodominant epitopes, which were found in seven fragments covering amino acid residues 35-81, 111-161, 423-453,462-491,531-577,616-669, 678-732.
goose parvovirus capsid protein prediction identification epitope
Tian-fei Yu Shu-li Shao Xing-jun Xu Ming Li Yuan Guo
College of Life Science and Agriculture Forestry University of Qiqihar Qiqihar, Heilongjiang Provinc College of Computer and Control Engineering University of Qiqihar Qiqihar, Heilongjiang Province, Ch
国际会议
成都
英文
88-92
2011-01-14（万方平台首次上网日期，不代表论文的发表时间）