Coordinated Nanobiosensor for Detection of Prostate Cancer Biomarker

摘要：

As part of an effort to develop coordinated biosensors, coiled coil peptides were designed, characterized and applied to fabricate coordinated biosensors for detection of prostate cancer biomarker (PCa) - prostate specific antigen (PSA). The coordinated nanobiosensor presented in this study is advantageous as the sensitivity of PSA detection is among the lowest reported, at 10.0 pg mL-1 and permits reuse of biosensors, as the biological components are robust with extended half-lives of activities.

关键词： Coordinated nanobiosensor Prostate specific antigen Coiled coil peptide Gold nanoelectrode

作者: Haibin Shi Joanne I. Yeh

作者单位: Department of Structural Biology, School of Medicine University of Pittsburgh Pittsburgh PA U.S.A. Department of Structural Biology and Department of Bioengineering, School of Medicine University of

会议类型: 国际会议

会议名称: 2011 International Conference on Medical Information and Bioengineering(2011年医药信息与生物工程国际会议 ICMIB 2011)

会议地点: 成都

会议语种:英文

页码: 152-154

在线出版日期: 2011-01-14（万方平台首次上网日期，不代表论文的发表时间）