Changes in the porcine peripheral blood mononuclear cell proteome induced by infection with highly virulent classical swine fever virus

摘要：

Classical swine fever (CSF) is a highly contagious swine disease causing major losses in the pig industry. Its causative agent, classical swine fever virus (CSFV), a small enveloped RNA virus with a single stranded positive RNA genome, belongs to the genus Pestivirus within the family Flaviviridae. The virus is known to have a particular tropism for cells of the immune system and for endothelial cells, and monocytes both in peripheral blood and in the various lymphoid organs are its major targets. Thereby, the clinical symptoms and pathologic alterations of CSF are characterized by hemorrhagic fever and immunosuppression.

作者: Jinfu Sun Zixue Shi Huancheng Guo Changchun Tu

作者单位: Institute of Biotechnology, College of Science, Northeastern University, Shenyang 110004,China Institute of Veterinary Sciences, Academy of Military Medical Sciences, 1068 Qinglong Road, Changchu Institute of Veterinary Sciences, Academy of Military Medical Sciences, 1068 Qinglong Road, Changchu

会议类型: 国际会议

会议名称: International Symposium on Bacterial Genomics,Evolution and Pathogenesis(病原菌基因组进化与致病机制国际研讨会)

会议地点: 江苏镇江

会议语种:英文

页码: 53-55

在线出版日期: 2010-11-30（万方平台首次上网日期，不代表论文的发表时间）