Immunosensor for Detecting Pulmonary Tuberculosis Markers in Human Serum

摘要：

A specific and high-sensitive lmmunosensor for detecting pulmonary tuberculosis (TB) markers in human serum is presented by miniaturizing array of microelectrodes via micro electro-mechanical system (MEMS) for multi-channel electrochemical measurement. The immunosensor is consisted of six Au disk working electrodes, one Au counter electrode and one Ag/AgCl reference electrode. Semi-insulating poly(ophenylenediamine)(PoPD) film was utilized to copolymerize and immobilize antigen at the arrayed Au electrodes. The selective recognition of antibody to the corresponding antigen is quantitatively detected by the peak current in the presence of the redox probe, FcCH2OH(FcM). Samples with antibody positive and antibody negative can be distinguished.

作者: Y. He R. Scheicher A. Grigoriev R. Ahuja S. Long Z. Huo1, Ming Liu

作者单位: Laboratory of nano-Fabrication and Novel Devices Integrated Technology, Institute of Microelectronic Condensed Matter Theory Group, Department of Physics and Astronomy, Box 516, Uppsala University, SE-

会议类型: 国际会议

会议名称: 2010 10th IEEE International Conference on Solid-State and Integrated Circuit Technology(第十届固态和集成电路技术国际会议 ICSICT-2010)

会议地点: 上海

会议语种:英文

页码: 1486-1488

在线出版日期: 2010-11-01（万方平台首次上网日期，不代表论文的发表时间）