Identification of differentially methylated regions (DMRs) by entropy

摘要：

1.Introduction DNA methylation, as an inartificial and inheritance epigenetic event, affects biological phenotype by inhibiting gene expression without changing the DNA sequence. The quantification of methylation difference across large numbers of samples and the identification of sample-specificity are important in genomic function analysis, and may provide an important reference for identifying specific drug targets. Differentially methylated regions (DMRs), as regions with diversity of methylation patterns, are regarded as possible functional regions in gene

作者: Hongbo Liu Jie Lv Jiang Zhu Yan Zhang

作者单位: College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China

会议类型: 国际会议

会议名称: 第四届全国生物信息学与系统生物学学术大会

会议地点: 杭州

会议语种:英文

页码: 106-108

在线出版日期: 2010-10-01（万方平台首次上网日期，不代表论文的发表时间）