Identification of disease domains underlying human genetic diseases: A Bayesian regression approach

摘要：

Introduction The identification of genetic risk factors underlying human inherited diseases represents one of the major research directions in human genetics studies, and has harvested plenty of concerns and explorations on the problem of identifying genes and their products that are responsible for specific diseases. Domains are structural units of proteins that often form functions, and thus exploring associations between protein domains and human inherited diseases will greatly improve our understanding of the pathogenesis of human complex diseases and further benefit the medical prevention, diagnosis and treatment of these diseases.

作者: Wangshu Zhang Yong Chen Fengzhu Sun Rui Jiang

作者单位: MOE Key laboratory of Bioinformatics and Bioinformatics Division, Department of Automation/TNLIST, T MOE Key laboratory of Bioinformatics and Bioinformatics Division, Department of Automation/TNLIST, T MOE Key laboratory of Bioinformatics and Bioinformatics Division, Department of Automation/TNLIST, T

会议类型: 国际会议

会议名称: 第四届全国生物信息学与系统生物学学术大会

会议地点: 杭州

会议语种:英文

页码: 109-111

在线出版日期: 2010-10-01（万方平台首次上网日期，不代表论文的发表时间）